Flights from Jersey to Luton and Glasgow were among 200 easyJet services cancelled at the weekend.
The budget airline blamed the cancellations on the disruption of staff shortages caused by Covid-19.
It said it had made efforts to combat the shortages by "rostering" standby crew on the weekend but was forced to make "additional cancellations" on Sunday and Monday.
62 flights from the UK have been cancelled on Monday (4 April)
"As a result of the current high rates of COVID infections across Europe, like all businesses easyJet is experiencing higher than usual levels of employee sickness.
We have taken action to mitigate this through the rostering of additional standby crew this weekend, however, with the current levels of sickness, we have also decided to make some cancellations in advance which were focused on consolidating flights where we have multiple frequencies so customers have more options to rebook their travel, often on the same day.
We are sorry for any inconvenience this may cause to customers on affected flights." - easyJet spokesperson.
The cancellations coincided with long queues at several UK airports as the Easter getaway began.
In some UK regions the school holidays began on Friday (1 April)
Heathrow say delays were down to Covid checks required by destination countries and "high passenger volumes".
Staff shortages because of coronavirus were also blamed - with that reason given for problems at Manchester Airport, which also struggled to deal with more people coming through their terminals.